Thanks to folks who have taken the time to respond to this query.  I have installed it from the dag repo as Troy suggested.  My user needs it to run SRIM (stopping power) calculations.  She tells me she runs it on the command line; something like 'wine srim ...' which supposedly does not invoke the gui.

Thanks again!
 

Daniel Widyono wrote:
> Just for anecdotal evidence, I use Picasa a lot on RHEL5x and previously on
> RHEL4x (Picasa for linux really is running under wine, packaged just for
> Picasa's use).
> 
> Only two minor issues:
> 
> 	sending photos through e-mail breaks when I use mutt because of the
> 	spaces in the pathnames
> 
> 	I have to work around the memory mapping issue with wine and modern
> 	distros:
> 		http://wiki.winehq.org/PreloaderPageZeroProblem
> 
> You could perhaps reduce the priority with a wine wrapper script.  I don't
> run this on servers, only on a desktop.  YMMV.
> 
> Regards,
> Dan W.
> 
> On Fri, Oct 03, 2008 at 03:21:32PM -0500, Ken Teh wrote:
>> Are they any problems running the wine emulator on SL5x?  I recall wine
>> used to be part of RedHat's distributions.  But, I dont see it in SL5x. Is
>> or was there a reason why it was left out? It appears to be part of the
>> EPEL repo which I am not familiar with.
>>
>> One of my users wants it on a server.  I'm reluctant to install it if it
>> will hang up the server.  I've never used it myself.  I've played around
>> with VMWare and while it works, there were the occasional hiccups. Which
>> is ok if it's your own machine.  Not so good on a multi-user server.
>>
>> I'd appreciate any advice.  Thanks!